TGF beta 1 (DGR12426) Rabbit mAb (PBS Only)
Product Name :
TGF beta 1 (DGR12426) Rabbit mAb (PBS Only)
Cat.No.:
db13117-PBS
Synonyms :
Tgfb; Tgfb-1; TGFbeta1; TGF-beta1
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:PBS Only
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Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. Mice lacking a functional copy of this gene develop severe multifocal inflammatory disease, yolk sac defects and colon cancer. [provided by RefSeq, Aug 2016]
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Immunogen
Recombinant protein of mouse TGF beta 1
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Gene ID
21803
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Swiss Prot
P04202
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Synonyms
Tgfb; Tgfb-1; TGFbeta1; TGF-beta1
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Reactivity
Human,Mouse,Rat
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Application
WB
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Recommended dilution
WB: 1:1000
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Calculated MW
44 kDa
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Observed MW
44 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR12426
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
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Western blot detection of TGF beta 1 in Jurkat,C6 cell lysates using
db13117(1:1000 diluted).
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期:现货
For research use only. Not intended for diagnostic.