p27 KIP 1单克隆抗体(DGR33528) | 高特异性&高亲和力

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Recombinant DGRmAb^®

p27 KIP 1 (DGR33528) Rabbit mAb (PBS Only)

db13119-PBS

Datasheet

Product Name : p27 KIP 1 (DGR33528) Rabbit mAb (PBS Only)

Cat.No.: db13119-PBS

Synonyms : KIP1; MEN4; CDKN4; MEN1B; P27KIP1

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]
Immunogen Recombinant protein of human p27 KIP 1
Gene ID 1027
Swiss Prot P46527
Synonyms KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Reactivity Human
Application WB
Recommended dilution WB: 1:1000-1:5000
Calculated MW 22 kDa
Observed MW 27 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR33528
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

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