IGF-I receptor alpha (DGR32099) Rabbit mAb (PBS Only)
Product Name :
IGF-I receptor alpha (DGR32099) Rabbit mAb (PBS Only)
Cat.No.:
db13134-PBS
Synonyms :
IGFR; CD221; IGFIR; JTK13; IGF1R
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation:PBS Only
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Background
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
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Immunogen
Recombinant protein of human IGF-I receptor alpha
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Gene ID
3480
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Swiss Prot
P08069
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Synonyms
IGFR; CD221; IGFIR; JTK13; IGF1R
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Reactivity
Human
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Application
WB, IHC-P
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Recommended dilution
WB: 1:1000
IHC-P: 1:200-1:500
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Observed MW
140 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR32099
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
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Immunohistochemical analysis of paraffin-embedded Immunohistochemistry analysis of human lung cancer using
db13134
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期:现货
For research use only. Not intended for diagnostic.