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Bax (DGR14973) Rabbit mAb (PBS Only)
db13145-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human Bax
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Gene ID
581
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Swiss Prot
Q07812
- Synonyms BCL2L4
- Reactivity Human,Mouse,Rat
- Application WB, IP
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Recommended dilution
WB: 1:1000
IP: 1:50 - Calculated MW 21 kDa
- Observed MW 21 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14973
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot detection of Bax in C6,3T3,Hela cell lysates using Bax antibody(1:1000 diluted).
订购信息
- Package Price (RMB)
- 100μg 4498
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
