Prothrombin (DGR33407) Rabbit mAb (PBS Only)
Product Name :
Prothrombin (DGR33407) Rabbit mAb (PBS Only)
Cat.No.:
db13158-PBS
Synonyms :
PT; THPH1; RPRGL2
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
This gene encodes the prothrombin protein (also known as coagulation factor II). This protein is proteolytically cleaved in multiple steps to form the activated serine protease thrombin. The activated thrombin enzyme plays an important role in thrombosis and hemostasis by converting fibrinogen to fibrin during blood clot formation, by stimulating platelet aggregation, and by activating additional coagulation factors. Thrombin also plays a role in cell proliferation, tissue repair, and angiogenesis as well as maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in this gene lead to various forms of thrombosis and dysprothrombinemia. Rapid increases in cytokine levels following coronavirus infections can dysregulate the coagulation cascade and produce thrombosis, compromised blood supply, and organ failure. [provided by RefSeq, May 2020]
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Immunogen
A synthetic peptide of human Prothrombin
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Gene ID
2147
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Swiss Prot
P00734
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Synonyms
PT; THPH1; RPRGL2
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Reactivity
Human
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Application
WB
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Recommended dilution
WB: 1:1000-1:5000
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Calculated MW
70 kDa
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Observed MW
70 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR33407
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期：现货
For research use only. Not intended for diagnostic.
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