Bcl10单克隆抗体(DGR33396) | 高特异性&高亲和力

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Recombinant DGRmAb^®

Bcl10 (DGR33396) Rabbit mAb (PBS Only)

db13168-PBS

Datasheet

Product Name : Bcl10 (DGR33396) Rabbit mAb (PBS Only)

Cat.No.: db13168-PBS

Synonyms : CLAP; mE10; CIPER; IMD37; c-E10; CARMEN

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated PBS Only

Background This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Immunogen A synthetic peptide of human Bcl10
Gene ID 8915
Swiss Prot O95999
Synonyms CLAP; mE10; CIPER; IMD37; c-E10; CARMEN
Reactivity Human
Application WB, FC
Recommended dilution WB: 1:1000-1:5000
FC: 1:200-1:1000
Calculated MW 26 kDa
Observed MW 26 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR33396
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

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