SHP1 (DGR11492) Rabbit mAb
Product Name :
SHP1 (DGR11492) Rabbit mAb
Cat.No.:
db13173
Synonyms :
HCP; HCPH; SHP1; SHP-1; HPTP1C; PTP-1C; SHP-1L; SH-PTP1
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
-
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
-
Immunogen
A synthetic peptide of human SHP1
-
Gene ID
5777
-
Swiss Prot
P29350
-
Synonyms
HCP; HCPH; SHP1; SHP-1; HPTP1C; PTP-1C; SHP-1L; SH-PTP1
-
Reactivity
Human
-
Application
WB, IHC-P, ICC/IF, FC
-
Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:500-1:2000
ICC/IF: 1:200-1:500
FC: 1:10-1:100
-
Calculated MW
68 kDa
-
Observed MW
68 kDa
-
Host species
Rabbit
-
Clonality
Monoclonal
-
Clonality No.
DGR11492
-
Isotype
IgG
-
Purity
Affinity Purification
-
Conjugation
Un-conjugated
-
Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
×
-
Western blot detection of SHP1 in Jurkat cell lysates using SHP1 antibody(1:500 diluted).
-
Immunohistochemical analysis of paraffin-embedded human tonsil using db13173 antibody.
订购信息
-
Package
Price (RMB)
-
10μL
398
-
20μL
698
-
50μL
1398
-
100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.