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BACE1 (DGR16149) Rabbit mAb (PBS Only)
db13283-PBS
Datasheet

Product Name : BACE1 (DGR16149) Rabbit mAb (PBS Only)

Cat.No.: db13283-PBS

Synonyms : ASP2; Bace; C76936

Application:

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Conjugation/Formulation:PBS Only

  • Background This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. Homozygous knockout mice for this gene exhibit a wide range of nervous system defects, growth retardation, metabolic abnormalities, and increased neonatal lethality. [provided by RefSeq, Nov 2015]
  • Immunogen Recombinant protein of mouse BACE1
  • Gene ID 23821
  • Swiss Prot P56818
  • Synonyms ASP2; Bace; C76936
  • Reactivity Human,Mouse,Rat
  • Application WB, IHC-P, IP
  • Recommended dilution WB: 1:1000
    IHC-P: 1:50
    IP: 1:50
  • Calculated MW 56 kDa
  • Observed MW 70 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR16149
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/ml
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
  • Western blot detection of BACE1 in Rat Brain lysates using BACE1 antibody(1:1000 diluted).
  • Western blot analysis of extracts from Mouse brain tissue using db13283
订购信息
  • Package Price (RMB)
  • 100μg 4498
  • 货期:现货
For research use only. Not intended for diagnostic.