Tissue Factor Pathway Inhibitor单克隆抗体(DGR32615) | 高特异性&高亲和力

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Recombinant DGRmAb^®

Tissue Factor Pathway Inhibitor (DGR32615) Rabbit mAb (PBS Only)

db13329-PBS

Datasheet

Product Name : Tissue Factor Pathway Inhibitor (DGR32615) Rabbit mAb (PBS Only)

Cat.No.: db13329-PBS

Synonyms : EPI; TFI; LACI; TFPI1

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016]
Immunogen A synthetic peptide of human TFPI
Gene ID 7035
Swiss Prot P10646
Synonyms EPI; TFI; LACI; TFPI1
Reactivity Human
Application WB
Recommended dilution WB: 1:1000-1:5000
Calculated MW 35 kDa
Observed MW 40-55 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR32615
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

Western blot detection of TFPI in A549,MCF-7 cell lysates using TFPI antibody(1:1000 diluted).

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