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ICAD (DGR13646) Rabbit mAb (PBS Only)
db13371-PBS
Datasheet
Product Name : ICAD (DGR13646) Rabbit mAb (PBS Only)
Cat.No.: db13371-PBS
Synonyms : DFF1; ICAD; DFF-45
Application：
Reactivity : Human, Mouse, Rat
Host species : Rabbit
Conjugation/Formulation：PBS Only
- Background Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human ICAD
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Gene ID
1676
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Swiss Prot
O00273
- Synonyms DFF1; ICAD; DFF-45
- Reactivity Human,Mouse,Rat
- Application WB
- Recommended dilution WB: 1:2000-1:20000
- Calculated MW 37 kDa
- Observed MW 45 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR13646
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot detection of ICAD in Rat Brain,MCF7,C6 cell lysates using db13371(1:1000 diluted).
订购信息
- Package Price (RMB)
- 100μg 5798
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
