Ku80单克隆抗体(DGR32655) | 高特异性&高亲和力

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Recombinant DGRmAb^®

Ku80 (DGR32655) Rabbit mAb (PBS Only)

db13397-PBS

Datasheet

Product Name : Ku80 (DGR32655) Rabbit mAb (PBS Only)

Cat.No.: db13397-PBS

Synonyms : KU80; KUB2; Ku86; NFIV; KARP1; KARP-1

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated PBS Only

Background The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human Ku80
Gene ID 7520
Swiss Prot P13010
Synonyms KU80; KUB2; Ku86; NFIV; KARP1; KARP-1
Reactivity Human
Application WB, IHC-P, FC
Recommended dilution WB: 1:1000
IHC-P: 1:200-1:500
FC: 1:100
Calculated MW 83 kDa
Observed MW 83 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR32655
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

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