Mre11单克隆抗体(DGR19407) | 高特异性&高亲和力

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Recombinant DGRmAb^®

Mre11 (DGR19407) Rabbit mAb (PBS Only)

db13499-PBS

Datasheet

Product Name : Mre11 (DGR19407) Rabbit mAb (PBS Only)

Cat.No.: db13499-PBS

Synonyms : ATLD; HNGS1; MRE11A; MRE11B

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Immunogen Recombinant protein of human Mre11
Gene ID 4361
Swiss Prot P49959
Synonyms ATLD; HNGS1; MRE11A; MRE11B
Reactivity Human,Mouse,Rat
Application WB, IHC-P, FC
Recommended dilution WB: 1:1000
IHC-P: 1:200-1:2000
FC: 1:200-1:500
Calculated MW 81 kDa
Observed MW 81 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR19407
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

Western blot detection of Mre11 in K562,Rat Brain,C6,3T3,Hela cell lysates using db13499(1:1000 diluted).
Immunohistochemical analysis of paraffin-embedded human lung cancer using db13499

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