Insulin (DGR31615) Rabbit mAb (PBS Only)
Product Name :
Insulin (DGR31615) Rabbit mAb (PBS Only)
Cat.No.:
db13712-PBS
Synonyms :
IDDM; ILPR; IRDN; IDDM1; IDDM2; PNDM4; MODY10
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes diabetes mellitus, maturity-onset diabetes of the young type 10 and hyperproinsulinemia. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq, May 2020]
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Immunogen
A synthetic peptide of human Insulin
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Gene ID
3630
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Swiss Prot
P01308
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Synonyms
IDDM; ILPR; IRDN; IDDM1; IDDM2; PNDM4; MODY10
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Reactivity
Human
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Application
IHC-P
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Calculated MW
12 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR31615
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/mL
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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可询价
- 货期：现货
For research use only. Not intended for diagnostic.
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