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CDK4 (DGR15767) Rabbit mAb (PBS Only)
db13778-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008]
- Immunogen Recombinant protein of human Cdk4
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Gene ID
1019
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Swiss Prot
P11802
- Synonyms CMM3; PSK-J3
- Reactivity Human,Mouse,Rat
- Application WB, ICC/IF, IP
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Recommended dilution
WB: 1:1000
ICC/IF: 1:100-1:200
IP: 1:50 - Calculated MW 34 kDa
- Observed MW 34 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR15767
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from K562,C6,3T3,HeLa cells using db13778
订购信息
- Package Price (RMB)
- 100μg 5798
- 货期：现货
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For research use only. Not intended for diagnostic.
