Product Name : Phospho-AMPK alpha 1 (Thr183)/AMPK alpha 2 (Thr172) (DGR18480) Rabbit mAb (PBS Only)
Cat.No.: db13913-PBS
Synonyms : AMPK; AMPKa1
Reactivity : Human, Mouse, Rat
Host species : Rabbit
Conjugation/Formulation：PBS Only
- Background The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic phosphopeptide corresponding to residues surrounding Thr183/Thr172 of human AMPK alpha 1/AMPK alpha 2
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Gene ID
5562
-
Swiss Prot
P54646
- Synonyms AMPK; AMPKa1
- Reactivity Human,Mouse,Rat
- Application WB
- Calculated MW 64,62 kDa
- Observed MW 62 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR18480
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
-
Western blot analysis of extracts from U2OS cells using db13913 at 1:1000.
- Package Price (RMB)
- 100μg 4498
- 货期：现货
