Product Name : Phospho-TGF beta Receptor II (Ser225) (DGR16007) Rabbit mAb (PBS Only)
Cat.No.: db13939-PBS
Synonyms : AAT3; FAA3; LDS2; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TGFR-2; TGFbeta-RII
Reactivity : Human
Host species : Rabbit
Conjugation/Formulation：PBS Only
- Background The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Aug 2017]
- Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser225 of human TGF beta Receptor II
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Gene ID
7048
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Swiss Prot
P37173
- Synonyms AAT3; FAA3; LDS2; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TGFR-2; TGFbeta-RII
- Reactivity Human
- Application WB
- Recommended dilution WB: 1:1000-1:5000
- Calculated MW 65 kDa
- Observed MW 85 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR16007
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from Rat heart tissue using db13939
- Package Price (RMB)
- 100μg 4498
- 货期：现货
