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Phospho-PKC zeta (Thr560) (DGR15836) Rabbit mAb (PBS Only)
db13941-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic phosphopeptide corresponding to residues surrounding Thr560 of human PKC zeta
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Gene ID
5590
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Swiss Prot
Q05513
- Synonyms PKC2; PKC-ZETA
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P
- Calculated MW 68 kDa
- Observed MW 68 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR15836
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from HeLa cells using db13941 at 1:1000.
订购信息
- Package Price (RMB)
- 100μg 7858
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
