Phospho-MLKL (Ser345) (DGR15309) Rabbit mAb (PBS Only)
Product Name :
Phospho-MLKL (Ser345) (DGR15309) Rabbit mAb (PBS Only)
Cat.No.:
db13947-PBS
Synonyms :
9130019I15Rik
Reactivity :
Mouse
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to lack protein kinase activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (Rip3), which is a key signaling molecule in necroptosis pathway. Knockout of this gene in mice showed that it is essential for necroptosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser345 of mouse MLKL
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Gene ID
74568
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Swiss Prot
Q9D2Y4
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Synonyms
9130019I15Rik
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Reactivity
Mouse
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Application
WB, IP
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Calculated MW
54 kDa
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Observed MW
54 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR15309
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/mL
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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100μg
4498
- 货期：现货
For research use only. Not intended for diagnostic.
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