您当前的位置：
Phospho-RPS6 (Ser240/Ser244) (DGR15114) Rabbit mAb (PBS Only)
db13958-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser240/Ser244 of human RPS6
-
Gene ID
6194
-
Swiss Prot
P62753
- Synonyms S6
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF, FC, IP
-
Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:200-1:1000
ICC/IF: 1:100
FC: 1:200-1:500
IP: 1:20-1:50 - Calculated MW 29 kDa
- Observed MW 32 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR15114
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
![]()
-
Western blot analysis of extracts from HCT116，C2C12，PC-12 cells using db13958
订购信息
- Package Price (RMB)
- 100μg 5798
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
