Phospho-SHP2 (Tyr542) (DGR14462) Rabbit mAb (PBS Only)
Product Name :
Phospho-SHP2 (Tyr542) (DGR14462) Rabbit mAb (PBS Only)
Cat.No.:
db13976-PBS
Synonyms :
CFC; NS1; JMML; SHP2; BPTP3; PTP2C; METCDS; PTP-1D; SH-PTP2; SH-PTP3
Reactivity :
Human,Mouse
Host species :
Rabbit
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Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding
Tyr542 of human SHP2
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Gene ID
5781
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Swiss Prot
Q06124
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Synonyms
CFC; NS1; JMML; SHP2; BPTP3; PTP2C; METCDS; PTP-1D; SH-PTP2; SH-PTP3
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Reactivity
Human,Mouse
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Application
WB, ICC/IF, IP
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Recommended dilution
WB: 1:1000
ICC/IF: 1:100-1:200
IP: 1:20-1:50
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Calculated MW
68 kDa
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Observed MW
68 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR14462
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
PBS Only
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Concentration
1mg/mL
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期：现货
For research use only. Not intended for diagnostic.
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