Phospho-Doublecortin (Ser297) (DGR14444) Rabbit mAb (PBS Only)
Product Name :
Phospho-Doublecortin (Ser297) (DGR14444) Rabbit mAb (PBS Only)
Cat.No.:
db13978-PBS
Synonyms :
Dbct
Reactivity :
Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase. Studies in knockout mice lacking this gene and the LIS1 gene suggest that the molecular interaction of these two genes is important in both in neuronal migration and neurogenesis, and there is a cortical role of this gene in nuclear translocation and positioning of the mitotic spindle in radial glial mitotic division. Multiple transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding
Ser297 of mouse Doublecortin
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Gene ID
13193
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Swiss Prot
O88809
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Synonyms
Dbct
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Reactivity
Mouse,Rat
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Application
WB, IHC-P, IP
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Calculated MW
41 kDa
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Observed MW
41 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR14444
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/mL
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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可询价
- 货期：现货
For research use only. Not intended for diagnostic.
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