Phospho-STAT5 (Tyr694) (DGR12680) Rabbit mAb (PBS Only)
Product Name :
Phospho-STAT5 (Tyr694) (DGR12680) Rabbit mAb (PBS Only)
Cat.No.:
db14090-PBS
Synonyms :
MGF; STAT5
Reactivity :
Human, Mouse
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding
Tyr694 of human STAT5
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Gene ID
6776
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Swiss Prot
P42229
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Synonyms
MGF; STAT5
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Reactivity
Human,Mouse
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Application
WB, IHC-P
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Calculated MW
91 kDa
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Observed MW
91 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR12680
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/mL
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期：现货
For research use only. Not intended for diagnostic.
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