CDK4单克隆抗体(DGR16501) | 高特异性&高亲和力

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Recombinant DGRmAb^®

CDK4 (DGR16501) Rabbit mAb (PBS Only)

db14093-PBS

Datasheet

Product Name : CDK4 (DGR16501) Rabbit mAb (PBS Only)

Cat.No.: db14093-PBS

Synonyms : CMM3; PSK-J3

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated PBS Only

Background The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human Cdk4
Gene ID 1019
Swiss Prot P11802
Synonyms CMM3; PSK-J3
Reactivity Human
Application WB, IHC-P, ICC/IF, FC
Recommended dilution WB: 1:1000-1:5000
IHC-P: 1:100-1:200
ICC/IF: 1:200-1:500
FC: 1:10-1:100
Calculated MW 34 kDa
Observed MW 34 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR16501
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

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