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Conjugation/Formulation：Un-conjugated
- Background This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq, Mar 2016]
- Immunogen Recombinant protein of human BIN1
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Gene ID
274
-
Swiss Prot
O00499
- Synonyms AMPH2; AMPHL; SH3P9
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF, FC
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Recommended dilution
WB: 1:1000
IHC-P: 1:100
ICC/IF: 1:100
FC: 1:50-1:100 - Calculated MW 65 kDa
- Observed MW 45-80 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14449
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of BIN1 in Rat Brain lysates using BIN1 antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded human tonsil using db14202 antibody. -
Immunofluorescent analysis of U87-MG cells using db14202 antibody (green), and DAPI (blue).
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
