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Conjugation/Formulation：Un-conjugated
- Background This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
- Immunogen Recombinant protein of human ErbB 4
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Gene ID
2066
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Swiss Prot
Q15303
- Synonyms HER4; ALS19; p180erbB4
- Reactivity Human,Mouse
- Application WB, IHC-P
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Recommended dilution
WB: 1:1000
IHC-P: 1:200-1:1000 - Calculated MW 147 kDa
- Observed MW 180 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR20611
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of ErbB 4 in Hela,A549,HL-60,U2OS,C6 cell lysates using ErbB 4 antibody(1:1000 diluted).
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
