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Glutathione S Transferase mu (DGR13678) Rabbit mAb

Product Name : Glutathione S Transferase mu (DGR13678) Rabbit mAb

Cat.No.: db14229

Synonyms : MU; H-B; GST1; GTH4; GTM1; MU-1; GSTM1-1; GSTM1a-1a; GSTM1b-1b

Application:

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Conjugation/Formulation:Un-conjugated

  • Background Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
  • Immunogen A synthetic peptide of human Glutathione S Transferase mu
  • Gene ID 2944
  • Swiss Prot P09488
  • Synonyms MU; H-B; GST1; GTH4; GTM1; MU-1; GSTM1-1; GSTM1a-1a; GSTM1b-1b
  • Reactivity Human,Mouse,Rat
  • Application WB
  • Recommended dilution WB: 1:1000-1:5000
  • Calculated MW 26 kDa
  • Observed MW 26 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR13678
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot detection of Glutathione S Transferase mu 1 in Jurkat,CHO-K1,Hela cell lysates using Glutathione S Transferase mu 1 antibody(1:500 diluted).
订购信息
  • Package Price (RMB)
  • 10μL 398
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.