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Phospho-AMPK alpha 1 (Ser496) (DGR31610) Rabbit mAb (PBS Only)
db14230-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser496 of human AMPK alpha 1
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Gene ID
5562
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Swiss Prot
Q13131
- Synonyms AMPK; AMPKa1
- Reactivity Human
- Application WB, ICC/IF
- Calculated MW 64 kDa
- Observed MW 64 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR31610
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot detection of AMPK alpha 1 (phospho-Ser496) in Ramos cell lysates using AMPK alpha 1 (phospho-Ser496) antibody(1:1000 diluted). -
Western blot analysis of extracts from Hela cells using db14230 at 1:1000. -
Immunofluorescent analysis of HeLa cells using db14230 antibody (green), and DAPI (blue).
订购信息
- Package Price (RMB)
- 100μg 7858
- 货期：现货
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For research use only. Not intended for diagnostic.
