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Conjugation/Formulation：Un-conjugated
- Background Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of H2B histone (By similarity), RPS7 and RPL18A. Prevents the cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains. May also import H2A, H3, H4 histones (By similarity), RPL4 and RPL6.
- Immunogen A synthetic peptide of human Importin 9
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Gene ID
55705
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Swiss Prot
Q96P70
- Synonyms Imp9
- Reactivity Human,Mouse
- Application WB, IHC-P, FC
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Recommended dilution
WB: 1:1000
IHC-P: 1:50-1:100
FC: 1:200-1:1000 - Calculated MW 115 kDa
- Observed MW 115 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR11533
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of Importin 9/RANBP9 in Jurkat,Hela cell lysates using Importin 9/RANBP9(1:1000 diluted). -
Western blot analysis of extracts from SCC-9 cells and Mouse kidney tissue using db14232 at 1:1000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
