Product Name : Phospho-ATP citrate lyase (Thr447/Ser451) (DGR19620) Rabbit mAb (PBS Only)
Cat.No.: db14234-PBS
Synonyms : ACL; ATPCL; CLATP
Reactivity : Human, Mouse, Rat
Host species : Rabbit
Conjugation/Formulation：PBS Only
- Background ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014]
- Immunogen A synthetic phosphopeptide corresponding to residues surrounding Thr447/Ser451 of human ATP citrate lyase
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Gene ID
47
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Swiss Prot
P53396
- Synonyms ACL; ATPCL; CLATP
- Reactivity Human,Mouse,Rat
- Application WB
- Calculated MW 121 kDa
- Observed MW 121 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR19620
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot detection of Phospho-ATP citrate lyase (Thr447+Ser451) in K562 cell lysates using Phospho-ATP citrate lyase (Thr447+Ser451) antibody(1:1000 diluted).
- Package Price (RMB)
- 100μg 7858
- 货期：现货
