CACNA2D (DGR20774) Rabbit mAb (PBS Only)
Product Name :
CACNA2D (DGR20774) Rabbit mAb (PBS Only)
Cat.No.:
db14235-PBS
Synonyms :
CACNA2D
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
Calcium channels mediate the entry of calcium ions into the cell upon membrane polarization. This gene encodes the alpha-2/delta subunit of the voltage-dependent calcium channel complex. The complex consists of the main channel-forming subunit alpha-1, and auxiliary subunits alpha-2/delta, beta, and gamma. The auxiliary subunits function in the assembly and membrane localization of the complex, and modulate calcium currents and channel activation/inactivation kinetics. The subunit encoded by this gene undergoes post-translational cleavage to yield the extracellular alpha2 peptide and a membrane-anchored delta polypeptide. This subunit is a receptor for the antiepileptic drug, gabapentin. Mutations in this gene are associated with early infantile epileptic encephalopathy. Single nucleotide polymorphisms in this gene are correlated with increased sensitivity to opioid drugs. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
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Immunogen
Recombinant protein of human CACNA2D
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Gene ID
9254
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Swiss Prot
Q9NY47
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Synonyms
CACNA2D
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Reactivity
Human,Mouse,Rat
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Application
WB, IP
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Recommended dilution
WB: 1:1000-1:5000
IP: 1:10-1:100
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Calculated MW
130 kDa
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Observed MW
130 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR20774
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期：现货
For research use only. Not intended for diagnostic.
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