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Conjugation/Formulation：Un-conjugated
- Background This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14. [provided by RefSeq, Jul 2009]
- Immunogen A synthetic peptide of human EWSR1
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Gene ID
2130
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Swiss Prot
Q01844
- Synonyms EWS; EWS-FLI1; bK984G1.4
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF, FC
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Recommended dilution
WB: 1:2000-1:20000
IHC-P: 1:200-1:500
ICC/IF: 1:200-1:1000
FC: 1:100 - Calculated MW 69 kDa
- Observed MW 85 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR13497
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of EWSR1 in MCF7,3T3,Hela cell lysates using EWSR1 antibody(1:1000 diluted). -
Immunofluorescent analysis of HeLa cells using db14236 antibody (green), and DAPI (blue). -
Western blot analysis of EWSR1 in rat brain lysates using EWSR1 antibody(1:1000 diluted). -
Western blot analysis of extracts from C2C12 cells and Rat kidney，Rat heart tissue using db14236 at 1:6000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
