IL-10 (DGR20530) Rabbit mAb (PBS Only)
Product Name :
IL-10 (DGR20530) Rabbit mAb (PBS Only)
Cat.No.:
db14268-PBS
Synonyms :
CSIF; TGIF; GVHDS; IL-10; IL10A
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
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Immunogen
A synthetic peptide of human IL-10
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Gene ID
3586
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Swiss Prot
P22301
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Synonyms
CSIF; TGIF; GVHDS; IL-10; IL10A
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Reactivity
Human
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Application
WB, ICC/IF, FC
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Recommended dilution
WB: 1:1000-1:5000
ICC/IF: 1:50-1:200
FC: 1:100-1:500
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Calculated MW
21 kDa
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Observed MW
17 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR20530
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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100μg
4498
- 货期：现货
For research use only. Not intended for diagnostic.
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