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Sarcomeric Alpha Actinin (DGR20423) Rabbit mAb

Product Name : Sarcomeric Alpha Actinin (DGR20423) Rabbit mAb

Cat.No.: db14287

Synonyms : CMH23; CMD1AA

Application:

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Conjugation/Formulation:Un-conjugated

  • Background Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
  • Immunogen A synthetic peptide of human Sarcomeric Alpha Actinin
  • Gene ID 88
  • Swiss Prot P35609
  • Synonyms CMH23; CMD1AA
  • Reactivity Human,Mouse,Rat
  • Application WB, IHC-P
  • Recommended dilution WB: 1:2000-1:20000
    IHC-P: 1:100-1:200
  • Calculated MW 104 kDa
  • Observed MW 104 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR20423
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot analysis of extracts from Mouse heart tissue using db14287 at 1:1000.
订购信息
  • Package Price (RMB)
  • 10μL 398
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.