GCDH (DGR20344) Rabbit mAb
Product Name :
GCDH (DGR20344) Rabbit mAb
Cat.No.:
db14295
Synonyms :
GCD; ACAD5
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12. [provided by RefSeq, Mar 2013]
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Immunogen
A synthetic peptide of human GCDH
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Gene ID
2639
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Swiss Prot
Q92947
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Synonyms
GCD; ACAD5
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Reactivity
Human,Mouse,Rat
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Application
WB, FC
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Recommended dilution
WB: 1:1000-1:5000
FC: 1:50-1:100
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Calculated MW
48 kDa
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Observed MW
48 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR20344
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
×
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Western blot analysis of extracts from HepG2 cells using db14295 at 1:1000.
订购信息
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Package
Price (RMB)
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10μL
398
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.