您当前的位置：
Activin Receptor Type IA (DGR15002) Rabbit mAb (PBS Only)
db14310-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human Activin Receptor Type IA
-
Gene ID
90
-
Swiss Prot
Q04771
- Synonyms FOP; ALK2; SKR1; TSRI; ACTRI; ACVR1A; ACVRLK2
- Reactivity Human,Mouse,Rat
- Application WB, IP
- Calculated MW 57 kDa
- Observed MW 57 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR15002
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
![]()
订购信息
- Package Price (RMB)
- 100μg 4498
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
