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Conjugation/Formulation：Un-conjugated
- Background The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human RAB8A
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Gene ID
4218
-
Swiss Prot
P61006
- Synonyms MEL; RAB8
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF, FC
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:200-1:500
ICC/IF: 1:200-1:500
FC: 1:200 - Calculated MW 24 kDa
- Observed MW 24 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR11431
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of RAB8A in K562,C6,3T3,Hela cell lysates using RAB8A antibody(1:1000 diluted). -
Western blot analysis of extracts from MCF-7 cells using db14334 at 1:3000. -
Immunohistochemical analysis of paraffin-embedded human colon cancer using db14334 antibody. -
Immunofluorescent analysis of HeLa cells using db14334 antibody (green), and DAPI (blue).
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
