NCX1单克隆抗体(DGR20194) | 高特异性&高亲和力

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Recombinant DGRmAb^®

NCX1 (DGR20194) Rabbit mAb

db14342

年底大促

Datasheet

Product Name : NCX1 (DGR20194) Rabbit mAb

Cat.No.: db14342

Synonyms : NCX1

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM, Apr 2004]
Immunogen A synthetic peptide of human NCX1
Gene ID 6546
Swiss Prot P32418
Synonyms NCX1
Reactivity Human,Mouse,Rat
Application WB
Recommended dilution WB: 1:1000-1:5000
Calculated MW 109 kDa
Observed MW 109 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR20194
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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