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BAP1 (DGR20699) Rabbit mAb
db14398
Datasheet
- Background This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013]
- Immunogen Recombinant protein of human BAP1
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Gene ID
8314
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Swiss Prot
Q92560
- Synonyms UCHL2; hucep-6; HUCEP-13
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, FC
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Recommended dilution
WB: 1:1000
IHC-P: 1:100
FC: 1:50-1:100 - Calculated MW 80 kDa
- Observed MW 95 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR20699
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of BAP1 in Hela,A549,HL-60,U2OS cell lysates using BAP1 antibody(1:1000 diluted). -
Western blot analysis of extracts from A431 cells using db14398 at 1:1000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
