DAP12 (DGR19779) Rabbit mAb (PBS Only)
Product Name :
DAP12 (DGR19779) Rabbit mAb (PBS Only)
Cat.No.:
db14449-PBS
Synonyms :
DAP12; KARAP; PLOSL
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation：PBS Only
-
Background
This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010]
-
Immunogen
A synthetic peptide of human DAP12
-
Gene ID
7305
-
Swiss Prot
O43914
-
Synonyms
DAP12; KARAP; PLOSL
-
Reactivity
Human
-
Application
WB, ICC/IF, FC
-
Calculated MW
12 kDa
-
Observed MW
12 kDa
-
Host species
Rabbit
-
Clonality
Monoclonal
-
Clonality No.
DGR19779
-
Isotype
IgG
-
Purity
Affinity Purification
-
Conjugation
Un-conjugated
-
Concentration
1 mg/mL
-
Formulation
PBS Only
-
Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
-
Package
Price (RMB)
-
100μg
4498
- 货期：现货
For research use only. Not intended for diagnostic.
浙公网安备 33010602008812号