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SHP2 (DGR19305) Rabbit mAb (PBS Only)
db14530-PBS
Datasheet
Buffer&Conjugation
- Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016]
- Immunogen Recombinant protein of human SHP2
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Gene ID
5781
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Swiss Prot
Q06124
- Synonyms CFC; NS1; JMML; SHP2; BPTP3; PTP2C; METCDS; PTP-1D; SH-PTP2; SH-PTP3
- Reactivity Human,Mouse,Rat
- Application WB, IP
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Recommended dilution
WB: 1:1000-1:5000
IP: 1:20-1:50 - Calculated MW 68 kDa
- Observed MW 68 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR19305
- Isotype IgG
- Purity Affinity Purification
- Conjugation PBS Only
- Concentration 1mg/mL
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from HeLa cells using db14530
订购信息
- Package Price (RMB)
- 100μg 5798
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
