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AMPK gamma 1 (DGR19961) Rabbit mAb (PBS Only)
db14570-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human AMPK gamma 1
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Gene ID
5571
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Swiss Prot
P54619
- Synonyms AMPKG
- Reactivity Human, Mouse, Rat
- Application WB, FC, IP
- Calculated MW 38 kDa
- Observed MW 38 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR19961
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot detection of AMPK gamma 1 in CHO-K1,C6,Jurkat cell lysates using AMPK gamma 1 antibody(1:500 diluted). -
Western blot analysis of extracts from Rat heart，Mouse brain tissue using db14570 at 1:1000.
订购信息
- Package Price (RMB)
- 100μg 7858
- 货期：现货
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For research use only. Not intended for diagnostic.
