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ErbB 4 (DGR19011) Rabbit mAb (PBS Only)
db14580-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human ErbB 4
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Gene ID
2066
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Swiss Prot
Q15303
- Synonyms HER4; ALS19; p180erbB4
- Reactivity Human,Mouse,Rat
- Application WB, FC
- Calculated MW 147 kDa
- Observed MW 180 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR19011
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from Mouse brain tissue using db14580 at 1:1000.
订购信息
- Package Price (RMB)
- 10μg 2598
- 100μg 7858
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
