Apolipoprotein B单克隆抗体(DGR18910) | 高特异性&高亲和力

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Recombinant DGRmAb^®

Apolipoprotein B (DGR18910) Rabbit mAb (PBS Only)

db14604-PBS

Datasheet

Product Name : Apolipoprotein B (DGR18910) Rabbit mAb (PBS Only)

Cat.No.: db14604-PBS

Synonyms : FLDB; LDLCQ4; apoB-48; apoB-100

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated PBS Only

Background This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human Apolipoprotein B
Gene ID 338
Swiss Prot P04114
Synonyms FLDB; LDLCQ4; apoB-48; apoB-100
Reactivity Human
Application WB
Calculated MW 516 kDa
Observed MW 516 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR18910
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/mL
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

Western blot analysis of extracts from Human plasma tissue using db14604 at 1:1000.

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