Proteasome 20S LMP2 (DGR18898) Rabbit mAb (PBS Only)
Product Name :
Proteasome 20S LMP2 (DGR18898) Rabbit mAb (PBS Only)
Cat.No.:
db14614-PBS
Synonyms :
LMP2; PSMB6i; RING12; beta1i
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. [provided by RefSeq, Mar 2010]
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Immunogen
A synthetic peptide of human Proteasome 20S LMP2
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Gene ID
5698
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Swiss Prot
P28065
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Synonyms
LMP2; PSMB6i; RING12; beta1i
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Reactivity
Human
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Application
WB, ICC/IF, FC, IP
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Calculated MW
23 kDa
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Observed MW
23 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR18898
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/mL
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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10μg
1498
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100μg
4498
- 货期：现货
For research use only. Not intended for diagnostic.
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