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CYFIP1 (DGR13325) Rabbit mAb (PBS Only)
db14678-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background This gene encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization.This protein also interacts with the Fragile X mental retardation protein (FMRP) and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including this gene is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of this gene has been observed in various human cancers and the encoded protein may inhibit tumor invasion. [provided by RefSeq, May 2017]
- Immunogen A synthetic peptide of human CYFIP1
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Gene ID
23191
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Swiss Prot
Q7L576
- Synonyms SHYC; SRA1; SRA-1; P140SRA-1
- Reactivity Human,Mouse,Rat
- Application WB, ICC/IF, FC
- Calculated MW 145 kDa
- Observed MW 145 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR13325
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot detection of CYFIP1 in K562,Rat Brain,C6,3T3,Hela cell lysates using CYFIP1 antibody(1:1000 diluted). -
Immunofluorescence analysis of HeLa cells labelling CYFIP1 with db14678.
The cells were fixed with cold 100% methanol (10min, 4℃) and blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween 20 for 1h. The cells were then incubate with db14678 (1:50) at room temprature for 1h, followed by a further incubation at room temperature for 45min with Goat Anti Rabbit lgG (H+L)-AF488 db10005, shown in green). Nuclear DNA was labeled in blue with DAPI.
Control: Secondary antibody only.
订购信息
- Package Price (RMB)
- 10μg 2598
- 100μg 7858
- 货期：现货
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For research use only. Not intended for diagnostic.
