Cdc6单克隆抗体(DGR12822) | 高特异性&高亲和力

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Recombinant DGRmAb^®

Phospho-Cdc6 (Ser106) (DGR12822) Rabbit mAb (PBS Only)

db14791-PBS

Datasheet

Product Name : Phospho-Cdc6 (Ser106) (DGR12822) Rabbit mAb (PBS Only)

Cat.No.: db14791-PBS

Synonyms : CDC18L; HsCDC6; MGORS5; HsCDC18

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated PBS Only

Background The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser106 of human Cdc6
Gene ID 990
Swiss Prot Q99741
Synonyms CDC18L; HsCDC6; MGORS5; HsCDC18
Reactivity Human
Application WB
Recommended dilution WB: 1:1000
Calculated MW 63 kDa
Observed MW 63 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR12822
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

Western blot detection of Phospho-Cdc6 (Ser106) in Jurkat cell lysates using db14791(1:1000 diluted).

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