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CEACAM1 (DGR16802) Rabbit mAb

Product Name : CEACAM1 (DGR16802) Rabbit mAb

Cat.No.: db14794

Synonyms : BGP; BGP1; BGPI

Application:

Reactivity : Human

Host species : Rabbit

Conjugation/Formulation:Un-conjugated

  • Background This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined. [provided by RefSeq, May 2010]
  • Immunogen A synthetic peptide of human CEACAM1
  • Gene ID 634
  • Swiss Prot P13688
  • Synonyms BGP; BGP1; BGPI
  • Reactivity Human
  • Application WB, IHC-P, IP
  • Recommended dilution WB: 1:2000-1:20000
    IHC-P: 1:50-1:100
    IP: 1:10-1:100
  • Calculated MW 58 kDa
  • Observed MW 120-160 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR16802
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot analysis of extracts from A549 cells using db14794 at 1:1000.
订购信息
  • Package Price (RMB)
  • 10μL 398
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.