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TAX1BP3 (DGR16701) Rabbit mAb (PBS Only)
db14817-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways; for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2017]
- Immunogen A synthetic peptide of human TAX1BP3
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Gene ID
30851
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Swiss Prot
O14907
- Synonyms TIP1; TIP-1
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, FC
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Recommended dilution
WB: 1:1000
IHC-P: 1:200-1:1000
FC: 1:100-1:200 - Calculated MW 14 kDa
- Observed MW 14 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR16701
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from C6 cells using db14817
订购信息
- Package Price (RMB)
- 100μg 4498
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
