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B Raf (DGR16691) Rabbit mAb (PBS Only)
db14821-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017]
- Immunogen A synthetic peptide of human B Raf
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Gene ID
673
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Swiss Prot
P15056
- Synonyms NS7; B-raf; BRAF1; RAFB1; B-RAF1
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, IP
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:100
IP: 1:20 - Calculated MW 84 kDa
- Observed MW 84 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR16691
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from Rat brain tissue using db14821
订购信息
- Package Price (RMB)
- 100μg 5798
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
