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Factor X (DGR16665) Rabbit mAb (PBS Only)
db14826-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq, Aug 2015]
- Immunogen Recombinant protein of human Factor X
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Gene ID
2159
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Swiss Prot
P00742
- Synonyms FX; FXA
- Reactivity Human
- Application WB, IHC-P
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Recommended dilution
WB: 1:2000-1:20000
IHC-P: 1:200-1:1000 - Calculated MW 55 kDa
- Observed MW 60 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR16665
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from Human fetal liver tissue using db14826
订购信息
- Package Price (RMB)
- 100μg 4498
- 货期：现货
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For research use only. Not intended for diagnostic.
